What is the recommended dose of prophylactic lidocaine administered prior to intubation?

The recommended dose of prophylactic lidocaine administered prior to intubation is 1.5 mg/kg IV/IO. This dosage is based on its efficacy in reducing the sympathetic response to intubation and minimizing potential discomfort associated with the procedure. Prophylactic administration of lidocaine is particularly beneficial in patients who are at higher risk for complications, such as increased intracranial pressure or those with a reactive airway.

Lidocaine acts by stabilizing neuronal membranes and inhibiting the transmission of impulses, thereby providing a local anesthetic effect that can suppress the airway reflexes during intubation. The 1.5 mg/kg dosage balances effectiveness with safety, ensuring adequate anesthetic coverage while minimizing the risk of side effects associated with higher doses. This consideration is essential, especially in critical care settings where intubation can be a high-stakes intervention.

Understanding the specific recommended dosing helps medical professionals ensure they apply best practices in airway management, enhancing patient comfort and safety during intubation procedures.